SDS-PAGE gel image showing Cynomolgus BST2 protein under reduced conditions with a prominent band between 25 kDa and 30 kDa, indicating high purity, alongside a molecular weight marker (lane MK) for reference.
  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Ile49-Ser163
  • Other Available Proteins:
    Finding available proteins...
Catalog #BST-CM202
Regular price $346.50
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Size
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Cynomolgus BST2 Protein (BST-CM202) Summary

Product Description

Recombinant Cynomolgus BST2 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ile49-Ser163.

Product Background

Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8/MARCH8 and the cargo receptor.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Cynomolgus BST2 Protein (BST-CM202) Specifications/Details

Protein
BST2
Synonyms
BST-2; HM1.24 antigen; CD317; BST2; NPC-A-7; PDCA-1; TETHERIN
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Ile49-Ser163
Molecular Weight
The protein has a predicted MW of 13.78 kDa. Due to glycosylation, the protein migrates to 15-30 kDa based on Bis-Tris PAGE result.
Product Tag
N-His

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Cynomolgus BST2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus BST2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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