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Human CXCL4 Protein (CXC-HM2L4) Summary
Product Description |
Recombinant Human CXCL4 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu32-Ser101. |
Product Background |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human CXCL4 Protein (CXC-HM2L4) Specifications/Details
Protein |
CXCL4 |
Synonyms |
PF-4; Oncostatin-A; CXCL4; SCYB4; Iroplact; MGC138298 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu32-Ser101 |
Molecular Weight |
The protein has a predicted MW of 34.5 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human CXCL4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human CXCL4 is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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