Name: Human IgG4 Fc Protein (IGG-HM004)
Brand: KactusBio
SKU: IGG-HM004-100UG
Price: 82.5 USD
Availability: InStock

Express System: HEK293
Product Tag: No Tag
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: The affinity constant of 0.10 uM as determined in SPR assay (Biacore T200).
Amino Acid Range: Glu99-Gly326
Other Available Proteins:

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Catalog #IGG-HM004

Size

100UG

500UG

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Human IgG4 Fc Protein (IGG-HM004) Summary

Product Description	Recombinant Human IgG4 Fc Protein is expressed from HEK293 without tag.It contains Glu99-Gly326.
Product Background	It is known as a IgG4-related disease and its differentiation is based on the analysis of IgG4 levels in the affected tissues. The IgG4-related disease is considered to be a generalized pathological process involving a wide spectrum of various disorders that may affect distant organs.
Product Category	Recombinant Protein / Antibody discovery / Fc receptors

Human IgG4 Fc Protein (IGG-HM004) Specifications/Details

Protein	IgG4 Fc
Synonyms	IGHG4
Accession	P01861
Species	Human
Biotinylated	no
Amino Acid Range	Glu99-Gly326
Molecular Weight	The protein has a predicted MW of 25.8 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 0.10 uM as determined in SPR assay (Biacore T200).
Product Tag	No Tag
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human FcRn, His Tag (Cat. FRN-HM101) captured on CM5 Chip via Anti-His Antibody can bind Human IgG4 Fc, No Tag with an affinity constant of 0.10 uM as determined in SPR assay (Biacore T200).
	Human IgG4 Fc on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Human FcRn, His Tag (Cat. FRN-HM101) on Anti-His-Biosensor can bind Human IgG4 Fc, No Tag with an affinity constant of 30.30 nM as determined in BLI assay.
	The purity of Human IgG4 Fc is greater than 90% as determined by SEC-HPLC.

Other Available Proteins:

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