Name: Human IgG4 Fc Protein (IGG-HM004)
Brand: KactusBio
SKU: IGG-HM004-100UG
Price: 82.5 USD
Availability: InStock

Express System: HEK293
Product Tag: No Tag
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 1.365 uM as determined in SPR assay (Biacore T200).
Amino Acid Range: Glu99-Gly326

Catalog #IGG-HM004

Size

100UG

500UG

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Human IgG4 Fc Protein (IGG-HM004) Summary

Product Description	Recombinant Human IgG4 Fc Protein is expressed from HEK293 without tag.It contains Glu99-Gly326.
Product Background	It is known as a IgG4-related disease and its differentiation is based on the analysis of IgG4 levels in the affected tissues. The IgG4-related disease is considered to be a generalized pathological process involving a wide spectrum of various disorders that may affect distant organs.
Product Category	Recombinant Protein / Antibody discovery / Fc receptors

Human IgG4 Fc Protein (IGG-HM004) Specifications/Details

Protein	IgG4 Fc
Synonyms	IGHG4
Accession	P01861
Species	Human
Biotinylated	no
Amino Acid Range	Glu99-Gly326
Molecular Weight	The protein has a predicted MW of 25.8 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 1.365 uM as determined in SPR assay (Biacore T200).
Product Tag	No Tag
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human FcRn, His Tag captured on CM5 Chip via Anti-His Antibody can bind Human IgG4 Fc, No Tag with an affinity constant of 1.365 uM as determined in SPR assay (Biacore T200).
	Human IgG4 Fc on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IgG4 Fc is greater than 95% as determined by SEC-HPLC.