Human MMP-2 Protein (pro form) (MMP-HM102)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Ile34-Cys660

Catalog: MMP-HM102

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Product Description Recombinant Human MMP-2 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ile34-Cys660.

Product Background

 Matrix metalloproteinase (MMP)-2 cleaves a broad spectrum of substrates, including extracellular matrix components (responsible for normal tissue remodeling) and cytokines (modulators of the inflammatory response to physiological insults such as tissue damage). MMP-2 expression is elevated in many cardiovascular pathologies (e.g., myocardial infarction, hypertensive heart disease) where tissue remodeling and inflammatory responses are perturbed.

Product Category

 Recombinant Protein

Target

 MMP-2
Synonyms Gelatinase A; MMP-2; PEX; CLG4; CLG4A; MONA; TBE-1; MMP-II

Gene/Protein ID

 P08253

Species

 Human

Exact Sequence

 Ile34-Cys660
Molecular Weight The protein has a predicted MW of 71.6 kDa. Due to glycosylation, the protein migrates to 72-75 kDa based on Tris-Bis PAGE result.

Product Tag

 N-His

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 25mM Tris, 150mM NaCl, 50% Glycerol (pH 7.5).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human MMP-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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