Name: Mouse IFN alpha 1 Protein (IFN-MM2A1)
Brand: KactusBio
SKU: IFN-MM2A1-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE
Activity: The affinity constant of 11.96 nM as determined in SPR assay (Biacore T200).
Amino Acid Range: Cys24-Lys189
Other Available Proteins:

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Catalog #IFN-MM2A1

Size

100UG

500UG

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Mouse IFN alpha 1 Protein (IFN-MM2A1) Summary

Product Description	Recombinant Mouse IFN alpha 1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Cys24-Lys189.
Product Background	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Mouse IFN alpha 1 Protein (IFN-MM2A1) Specifications/Details

Protein	IFN alpha 1
Synonyms	Interferon alpha-1/13;IFN-alpha-1/13;Interferon alpha-D;LeIF D; IFNalpha 1; IFN alpha1;IFNA1;IFN-alpha-1;Interferon alpha 1
Accession	P01572
Species	Mouse
Biotinylated	no
Amino Acid Range	Cys24-Lys189
Molecular Weight	The protein has a predicted MW of 45.88 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 11.96 nM as determined in SPR assay (Biacore T200).
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IFN alpha/beta R1, His Tag (Cat. IFN-HM4R1) captured on CM5 Chip via anti-his antibody can bind Mouse IFN alpha 1, hFc Tag with an affinity constant of 11.96 nM as determined in SPR assay (Biacore T200).
	Mouse IFN alpha 1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Biotinylated Mouse IFN alpha/beta R2, His-Avi Tag (Cat. IFN-MM1R2B) on Anti-His-Biosensor can bind Mouse IFN alpha 1, hFc Tag with an affinity constant of 5.44 nM as determined in BLI assay .
	Loaded Biotinylated Mouse IFN alpha/beta R1, His Tag on Streptavidin-Biosensor can bind Mouse IFN alpha 1, hFc Tag with an affinity constant of 1.00 µM as determined in BLI assay .
	Loaded Human IFN alpha/beta R1, His Tag (Cat. IFN-HM4R1) on Anti-His-Biosensor can bind Mouse IFN alpha 1, hFc Tag with an affinity constant of 0.25 µM as determined in BLI assay .

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