Mouse Kremen-2 Protein (KRE-MM102)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Exact Sequence: Gly25-Ser363

Catalog: KRE-MM102

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Product Description Recombinant Mouse Kremen-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly25-Ser363.

Product Background

Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy.

Product Category

Recombinant Protein

Target

Kremen-2
Synonyms KRM2; KREMEN2; Kremen-2; Dickkopf receptor 2
Accession

Species

Mouse

Exact Sequence

Gly25-Ser363
Molecular Weight The protein has a predicted MW of 37.4 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse Kremen-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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