Articles on GPCRS

G-protein coupled receptors (GPCRs) are pivotal targets in drug discovery due to their central role in cellular signaling. This category provides in-depth analysis of GPCR structures, signaling mechanisms, and advances in therapeutic targeting.



Featured Article

MRGPRX2: A Promising Target for Antibody Discovery in Allergy and Pain Disorders

Recent studies have shown that various drugs, including small molecules, opioids, and antibiotics, can activate MRGPRX2 (Mas-related G-protein coupled receptor X2), leading to mast cell degranulation and triggeringdrug hypersensitivity reactions.

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MRGPRX2: A Promising Target for Antibody Discovery in Allergy and Pain Disorders

October 28, 2024

6 min read

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