Name: Human SEZ6 Protein (SEZ-HM206)
Brand: KactusBio
SKU: SEZ-HM206-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human SEZ6, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-SEZ6 Antibody, hFc Tag with the EC50 of 23.1ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Leu20-His925

Catalog #SEZ-HM206

Size

100UG

500UG

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Product Description	Recombinant Human SEZ6 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu20-His925.
Product Background	Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.
Product Category	Recombinant Protein

Protein	SEZ6
Synonyms	SEZ-6; SEZ6; BSRPC; BSRP-C
Accession	Q53EL9-1
Species	Human
Biotinylated	no
Amino Acid Range	Leu20-His925
Molecular Weight	The protein has a predicted MW of 124.53 kDa. Due to glycosylation, the protein migrates to 140-200 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human SEZ6, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-SEZ6 Antibody, hFc Tag with the EC50 of 23.1ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human SEZ6, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-SEZ6 Antibody, hFc Tag with the EC50 of 23.1ng/ml determined by ELISA (QC Test).
	Human SEZ6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.