Human CD20 Protein-VLP (CD2-HM122)

  • Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized Human CD20 VLP at 5ug/ml (100ul/Well) on plate on the plate. Dose response curve for Ofatumumab, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Exact Sequence: Met1-Pro297

Catalog: CD2-HM122

$1,100.00
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Product Description Recombinant Human CD20 Protein-VLP is expressed from HEK293.It contains Met1-Pro297.

Product Background

B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.

Product Category

Recombinant Protein

Target

CD20 VLP
Synonyms MS4A1; CD20; MS4A-1; B1; Bp35; CD20 receptor; CD20S7; CVID5; LEU-16; Ly-44; MS4A2; S7

Gene/Protein ID

P11836-1

Species

Human

Exact Sequence

Met1-Pro297
Molecular Weight The target protein has a predicted MW of 34.3 kDa.

Activity

Immobilized Human CD20 VLP at 5ug/ml (100ul/Well) on plate on the plate. Dose response curve for Ofatumumab, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA (QC Test). See testing image for detail.

Express System

HEK293
Purity > 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in PBS, 300mM L-Arginine (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human CD20 VLP at 5ug/ml (100ul/Well) on plate on the plate. Dose response curve for Ofatumumab, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA (QC Test).
Immobilized Human CD20 VLP at 5ug/ml (100ul/Well) on plate on the plate. Dose response curve for Rituximab, hFc Tag with the EC50 of 13.2ng/ml determined by ELISA (QC Test).
Immobilized Human CD20 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Obinutuzumab, hFc Tag with the EC50 of 1.7ng/ml determined by ELISA.
The purity of Human CD20 VLP is greater than 95% as determined by SEC-HPLC.

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