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MRGPRX2: A Promising Target for Antibody Discovery in Allergy and Pain Disorders

Recent studies have shown that various drugs, including small molecules, opioids, and antibiotics, can activate MRGPRX2 (Mas-related G-protein coupled receptor X2), leading to mast cell degranulation and...

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A next-generation immunotherapy target TNFR2

February 10, 2023

5 min read

The tumor necrosis factor (TNF) superfamily has important physiological significance in immune surveillance, tumor regression, resistance to infection and hematopoiesis....

New Products February 2023

February 7, 2023

4 min read

Alkaline Phosphatase  Alkaline Phosphatase (ALP) likely represents the most frequently assayed enzyme in all of medicine. It is widely distributed...

GARP-TGF-β1 Monoclonal Antibody Clinical Trial Approved by FDA

January 23, 2023

3 min read

On January 4, 2023, Shanghai Jiyu Pharmaceutical announced that the IND application for its Class 1 drug JYB1907, GARP-TGF-β1 monoclonal...

Focus on hematoma target FLT3

January 9, 2023

6 min read

About FLT3 Fms-like tyrosine kinase 3 (FLT3) is also known as CD135 (Cluster of differentiation antigen 135) and FLK2 (Fetal...

DKK1: A Wnt Pathway Regulator

January 6, 2023

5 min read

DKK1 (Dickkopf-related protein 1, or Soggy) is a secreted glycoprotein that contains two conserved cysteine-rich domains CRD-1 and CRD-2 (also...

CD163 Protein

November 17, 2022

KACTUS offers human, mouse, and biotinylated CD163 protein.  The hemoglobin (Hb) scavenger receptor CD163, is a macrophage-specific protein involved in...

October Products

October 28, 2022

2 min read

KACTUS has developed the following new products to facilitate the latest innovations in drug development. Select a product category to...

Targeting Axl-GAS6—a new option for tumor therapy

September 12, 2022

4 min read

Tumor drug resistance is a major problem limiting the clinical efficacy of therapeutic drugs. Recently, an article published by a...

Potential Immunotherapy Target TM4SF1

September 5, 2022

5 min read

TM4SF1 (Transmembrane 4L six family member 1) is a member of the TM4SF subfamily in the Tetraspanin superfamily. It was...

GDF15-GFRAL breaks into the new drug track

July 12, 2022

7 min read

A variety of metabolic diseases that plague today's society, such as obesity, diabetes, cancer, etc., have yet to be solved....

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