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Rethinking Refolding: The Case for Mammalian-Expressed Single-Chain Trimer MHCs

For years, recombinant major histocompatibility complexes (MHCs) have been expressed in bacterial systems with in vitro refolding. While this preserves the native MHC sequence...

August 20, 2024
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AccuBase™: Base Editing Enzyme Advancing NK Cell Cancer Therapy

AccuBase™: Base Editing Enzyme Advancing NK Cell Cancer Therapy

July 31, 2024

3 min read

KACTUS, the strategic partner of Base Therapeutics, is the exclusive supplier of GMP-grade AccuBase™, the world’s first “off-the-shelf” cytosine base...

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IND Approval for Solid Tumor Therapy Using KACTUS Cas9 Enzyme

IND Approval for Solid Tumor Therapy Using KACTUS Cas9 Enzyme

July 24, 2024

4 min read

In a groundbreaking development for the biotech industry, KACTUS's GMP-grade Cas9 has critically helped Yizun Bio secure IND clearance for a universal...

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FDA New Guidelines Pave the Way for Gene Editing Drug Development

FDA New Guidelines Pave the Way for Gene Editing Drug Development

April 24, 2024

2 min read

FDA Official Guidelines On January 31, 2024, the FDA CBER officially released the "Human Gene Therapy Products Incorporating Human Genome...

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Base Editing Technology Leads a New Chapter in Drug Development

Base Editing Technology Leads a New Chapter in Drug Development

February 14, 2024

5 min read

Since its debut in 2016, base editing technology has opened up new perspectives and methods for drug development with its...

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RNP, an emerging powerful tool for gene delivery

RNP, an emerging powerful tool for gene delivery

February 2, 2024

5 min read

Through decades of rapid development, gene editing technology has officially entered the CRISPR 2.0 era, with new technologies such as...

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Empowering Gene Editing Therapy: The Atlas of Gene Editing Enzymes from KACTUS

Empowering Gene Editing Therapy: The Atlas of Gene Editing Enzymes from KACTUS

December 5, 2023

6 min read

Overview By leveraging its sophisticated ‘Structure Aided Design and Multiplex Screening (SAMS™)’ platform, along with extensive experience in process development...

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AccuBase™ Base Editor Enzyme: Globally In Stock Now

AccuBase™ Base Editor Enzyme: Globally In Stock Now

December 1, 2023

5 min read

Overview AccuBase™ is a new generation base editing tool independently developed by Base Therapeutics with exclusive global IP rights. AccuBase™ enzyme is...

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Global Release of the First Commercial Base Editor on the Market: AccuBase™

Global Release of the First Commercial Base Editor on the Market: AccuBase™

November 2, 2023

4 min read

KACTUS and Base Therapeutics announced their new strategic partnership to facilitate global manufacturing and sales of the GMP-grade base editor...

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