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MRGPRX2: A Promising Target for Antibody Discovery in Allergy and Pain Disorders

Recent studies have shown that various drugs, including small molecules, opioids, and antibiotics, can activate MRGPRX2 (Mas-related G-protein coupled receptor X2), leading to mast cell degranulation and...

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Fat Loss and Muscle Gain: Targeting the Activin Signaling Pathway

May 30, 2024

4 min read

In July 2023, Eli Lilly made a nearly $2 billion bet on Versanis' ActRII inhibitor, Bimagrumab, citing its ability to...

MSLN Targeted Drugs Entering the Fast Lane

February 29, 2024

5 min read

Since December 2023, there have been several positive updates about drugs targeting MSLN. On December 19th, RemeGen announced that the...

Deciphering LY6G6D - An Emerging Target in Colorectal Cancer

February 7, 2024

4 min read

Colorectal cancer (CRC) is recognized as one of the most common and life-threatening malignancies, with an increasing proportion of advanced...

Focusing on the Neuroendocrine Tumor Target SEZ6

January 2, 2024

4 min read

Neuroendocrine neoplasms/tumors (NENs or NETs) are rare tumors that originate from specialized cells called neuroendocrine cells. These cells have characteristics...

Butyrophilin (BTN) family: γδ T Cell Receptor Ligands, Immunomodulators and More

December 27, 2023

5 min read

Immunotherapy is an essential option for current disease treatment. However, most patients fail to respond adequately to existing immunotherapies, such...

The Role of Delta-like Ligand 3 (DLL3) in Targeted Therapy for Cancer

November 27, 2023

5 min read

On November 13, 2023, Legend Biotech officially announced that its wholly-owned subsidiary, Legend Biotech Ireland Limited, has entered into an...

Advancing Breast Cancer Research: Uniting for Progress on World Breast Cancer Research Day 2023

August 18, 2023

1 min read

Every year, on August 18th, the world comes together to observe World Breast Cancer Research Day—a day dedicated to raising...

Exploring the Role of MICA in Tumor Immunity and Targeted Therapies

July 6, 2023

4 min read

MICA, also known as MHC Class I Polypeptide-Related Sequence A, is a type I MHC molecule that is highly homologous...

Harnessing the Power of Wnt3a: Promoting Growth and Development of Organoids

June 29, 2023

3 min read

Organoids are a three-dimensional model established in vitro that is highly similar to tissues or organs in vivo, and can...

Breakout Tumor Target: DLL3

June 28, 2023

6 min read

At the ASCO annual meeting in 2023, Boehringer-Ingelheim disclosed the phase I clinical data of their bispecific antibody drug BI...

New target for colorectal cancer: GPA33

February 24, 2023

4 min read

Colorectal cancer (CRC) is the third most common tumor and the most common tumor of the digestive system. With the...

Potential drug target for tumors: CDCP1

February 21, 2023

5 min read

The process of tumor cell infiltration, adhesion and migration is an important research direction in the process of drug development....

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