News & Articles

FEATURED ARTICLE

MASP2 Antibody Successful in Phase III Clinical Trial

On December 19, 2024, Omeros announced that its pivotal Phase 3 clinical trial of the MASP2 antibody Narsoplimab (OMS721) in the treatment of TA-TMA (Transplant-Associated Thrombotic Microangiopathy) met its primary endpoint of overall survival (OS), with a 3-fold reduction in mortality risk [1]. Omeros stock surged 37% after the press release...

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MASP2 Antibody Successful in Phase III Clinical Trial

February 10, 2025

5 min read

On December 19, 2024, Omeros announced that its pivotal Phase 3 clinical trial of the MASP2 antibody Narsoplimab (OMS721) in...

Immunotherapy Target: CD19 Antigen

February 4, 2025

7 min read

CD19 remains a hot target in immunotherapy, driving innovation across a range of diseases. This is evidenced by recent approvals...

Emerging New Therapeutic Targets for Obesity

January 14, 2025

7 min read

Obesity is increasingly undermining human health. Obesity, a chronic metabolic disease, has significantly impacted the health and quality of life...

Activin Signaling Pathway: Therapeutic Potential Across Disease Frontiers

November 25, 2024

7 min read

What if a single cellular pathway could unlock new therapies for muscle regeneration, cancer, obesity, immune system regulation, and more?...

MRGPRX2: A Promising Target for Antibody Discovery in Allergy and Pain Disorders

October 28, 2024

5 min read

Recent studies have shown that various drugs, including small molecules, opioids, and antibiotics, can activate MRGPRX2 (Mas-related G-protein coupled receptor...

Fat Loss and Muscle Gain: Targeting the Activin Signaling Pathway

May 30, 2024

4 min read

In July 2023, Eli Lilly made a nearly $2 billion bet on Versanis' ActRII inhibitor, Bimagrumab, citing its ability to...

MSLN Targeted Drugs Entering the Fast Lane

February 29, 2024

5 min read

Since December 2023, there have been several positive updates about drugs targeting MSLN. On December 19th, RemeGen announced that the...

Deciphering LY6G6D - An Emerging Target in Colorectal Cancer

February 7, 2024

4 min read

Colorectal cancer (CRC) is recognized as one of the most common and life-threatening malignancies, with an increasing proportion of advanced...

Focusing on the Neuroendocrine Tumor Target SEZ6

January 2, 2024

4 min read

Neuroendocrine neoplasms/tumors (NENs or NETs) are rare tumors that originate from specialized cells called neuroendocrine cells. These cells have characteristics...

Butyrophilin (BTN) family: γδ T Cell Receptor Ligands, Immunomodulators and More

December 27, 2023

5 min read

Immunotherapy is an essential option for current disease treatment. However, most patients fail to respond adequately to existing immunotherapies, such...

The Role of Delta-like Ligand 3 (DLL3) in Targeted Therapy for Cancer

November 27, 2023

5 min read

  On November 13, 2023, Legend Biotech officially announced that its wholly-owned subsidiary, Legend Biotech Ireland Limited, has entered into...

Advancing Breast Cancer Research: Uniting for Progress on World Breast Cancer Research Day 2023

August 18, 2023

1 min read

Every year, on August 18th, the world comes together to observe World Breast Cancer Research Day—a day dedicated to raising...

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