Name: Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein (BCM-CM117)
Brand: KactusBio
SKU: BCM-CM117-100UG
Price: 346.5 USD
Availability: InStock

LISA binding curve for recombinant Cynomolgus BCMA protein with His tag, showing interaction with biotinylated human APRIL (trimer). Graph plots absorbance (OD450) vs. ligand concentration, demonstrating BCMA-APRIL binding activity.

Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein (BCM-CM117)

Biotinylated Cynomolgus BAFF (Trimer), His Tag captured on CM5 Chip via streptavidin can bind Cynomolgus BCMA, His Tag with an affinity constant of 1.40 µM as determined in SPR assay (Biacore T200).

Immobilized Cynomolgus BCMA, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human APRIL (Trimer), His Tag with the EC50 of 15.8 ng/ml determined by ELISA (QC Test).

Immobilized Cynomolgus BCMA, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-BCMA Antibody, hFc Tag with the EC50 of 3.2 ng/ml determined by ELISA.

Cynomolgus/Rhesus macaque BCMA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Loaded Biotinylated Human APRIL (Trimer), His-Avi Tag on Streptavidin-Biosensor can bind Cynomolgus BCMA, His Tag with an affinity constant of 5.75 nM as determined in BLI assay (Gator® Prime).

Loaded Anti-BCMA antibody on ProA-Biosensor can bind Cynomolgus BCMA, His Tag with an affinity constant of 8.99 nM as determined in BLI assay (Gator® Prime).

Loaded Biotinylated Cynomolgus BAFF (Trimer), His-Avi-Flag Tag on Streptavidin-Biosensor, can bind Cynomolgus BCMA, His Tag with an affinity constant of 1.69 µM as determined in BLI assay (Gator).

The purity of Cynomolgus/Rhesus macaque BCMA is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus BCMA, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human APRIL (Trimer), His Tag with the EC50 of 15.8 ng/ml determined by ELISA (QC Test). The affinity constant of 1.40 µM as determined in SPR assay (Biacore T200).
Amino Acid Range: Met1-Ala53

Catalog #BCM-CM117

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein (BCM-CM117) Summary

Product Description	Recombinant Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Ala53.
Product Background	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein (BCM-CM117) Specifications/Details

Protein	BCMA/TNFRSF17
Synonyms	CD269; TNFRSF17; BCMA; BCM; TNFRSF13A
Accession	A0A2K5UD97(Cynomolgus) / F7FFA0(Rhesus macaque)
Species	Cynomolgus/Rhesus macaque
Biotinylated	no
Amino Acid Range	Met1-Ala53
Molecular Weight	The protein has a predicted MW of 7.10 kDa. Due to glycosylation, the protein migrates to 13-23 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus BCMA, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human APRIL (Trimer), His Tag with the EC50 of 15.8 ng/ml determined by ELISA (QC Test). The affinity constant of 1.40 µM as determined in SPR assay (Biacore T200).
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Biotinylated Cynomolgus BAFF (Trimer), His Tag captured on CM5 Chip via streptavidin can bind Cynomolgus BCMA, His Tag with an affinity constant of 1.40 µM as determined in SPR assay (Biacore T200).
	Immobilized Cynomolgus BCMA, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human APRIL (Trimer), His Tag with the EC50 of 15.8 ng/ml determined by ELISA (QC Test).
	Immobilized Cynomolgus BCMA, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-BCMA Antibody, hFc Tag with the EC50 of 3.2 ng/ml determined by ELISA.
	Cynomolgus/Rhesus macaque BCMA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Biotinylated Human APRIL (Trimer), His-Avi Tag on Streptavidin-Biosensor can bind Cynomolgus BCMA, His Tag with an affinity constant of 5.75 nM as determined in BLI assay (Gator® Prime).
	Loaded Anti-BCMA antibody on ProA-Biosensor can bind Cynomolgus BCMA, His Tag with an affinity constant of 8.99 nM as determined in BLI assay (Gator® Prime).
	Loaded Biotinylated Cynomolgus BAFF (Trimer), His-Avi-Flag Tag on Streptavidin-Biosensor, can bind Cynomolgus BCMA, His Tag with an affinity constant of 1.69 µM as determined in BLI assay (Gator).
	The purity of Cynomolgus/Rhesus macaque BCMA is greater than 95% as determined by SEC-HPLC.