Name: Cynomolgus/Rhesus macaque CD19 Protein (CD1-CM119)
Brand: KactusBio
SKU: CD1-CM119-100UG
Price: 315.0 USD
Availability: InStock

Cynomolgus/Rhesus macaque CD19 Protein (CD1-CM119)

Express System: HEK293
Product Tag: N-His
Purity: >95% as determined by Bis-Tris PAGE
Activity: The affinity constant of 0.46 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gln21-Trp291

Catalog #CD1-CM119

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus/Rhesus macaque CD19 Protein is expressed from HEK293 with His tag at the N-terminus; It contains Gln21-Trp291.
Product Background	CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2 stores.
Product Category	Recombinant Protein

Target	CD19
Accession	A0A2K5W8L9
Species	Cynomolgus/Rhesus macaque
Biotinylated	no
Amino Acid Range	Gln21-Trp291
Molecular Weight	The protein has a predicted MW of 30.96 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 0.46 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	N-His
Express System	HEK293
Purity	>95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Anti-CD19 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus/Rhesus macaque CD19, His Tag with an affinity constant of 0.46 uM as determined in SPR assay (Biacore T200).
	Cynomolgus/Rhesus macaque CD19 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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