Biotinylated Human CDH17/Cadherin 17 Protein (CDH-HM417B)
Biotinylated Human CDH17/Cadherin 17 Protein (CDH-HM417B)
Biotinylated Human CDH17/Cadherin 17 Protein (CDH-HM417B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Biotinylated Human CDH17, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln23-Met787
Catalog #CDH-HM417B
Regular price $577.50
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Product Description

Recombinant Biotinylated Human CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln23-Met787.

Product Background

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

CDH17/Cadherin 17

Synonyms

Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16;

Accession

Species

Human

Biotinylated

yes

Amino Acid Range

Gln23-Met787

Molecular Weight

The protein has a predicted MW of 87.88 kDa. Due to glycosylation, the protein migrates to 105-120 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Biotinylated Human CDH17, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Biotinylated Human CDH17, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA. Immobilized Biotinylated Human CDH17, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA.
Biotinylated Human CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Loaded Anti-CDH17 Antibody, hFc-Avi Tag on ProA-Biosensor can bind Biotinylated Human CDH17, His-Avi Tag with an affinity constant of 1.27 pM as determined in BLI assay (Gator® Prime). Loaded Anti-CDH17 Antibody, hFc-Avi Tag on ProA-Biosensor can bind Biotinylated Human CDH17, His-Avi Tag with an affinity constant of 1.27 pM as determined in BLI assay (Gator® Prime).

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support@kactusbio.us

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