Biotinylated Human CDH17/Cadherin 17 Protein (CDH-HM417B)
Biotinylated Human CDH17/Cadherin 17 Protein (CDH-HM417B)
Biotinylated Human CDH17/Cadherin 17 Protein (CDH-HM417B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Biotinylated Human CDH17, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln23-Met787
Catalog #CDH-HM417B
Regular price $525.00
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Product Description
Recombinant Biotinylated Human CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln23-Met787.
Product Background
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Category
Recombinant Protein
Target
Biotinylated CDH17/Cadherin 17
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Gln23-Met787
Molecular Weight
The protein has a predicted MW of 87.88 kDa. Due to glycosylation, the protein migrates to 105-120 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Biotinylated Human CDH17, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA. See testing image for detail.
Product Tag
C-His-Avi
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Biotinylated Human CDH17, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA.
Biotinylated Human CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human CDH17 is greater than 95% as determined by SEC-HPLC.

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