Human CDH3/Cadherin 3 Protein (CDH-HM103)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Anti-CDH3 Antibody, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human CDH3, His Tag with the EC50 of 2.4ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Asp108-Gly654

Catalog: CDH-HM103

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Product Description Recombinant Human CDH3/Cadherin 3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp108-Gly654.

Product Background

Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been proved it could be a serum marker to monitor colorectal cancer. Inhibited CDH3 expression could upregulate E-cadherin, downregulated N-cadherin, which may control invasion and migration.

Product Category

Recombinant Protein

Target

CDH3/Cadherin 3
Synonyms Cadherin-3;Placental cadherin;P-cadherin;CDH3;CDHP;HJMD;PCAD;PCADP-cadherin;CAD3
Accession

Species

Human

Amino Acid Range

Asp108-Gly654
Molecular Weight The protein has a predicted MW of 64.32 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Anti-CDH3 Antibody, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human CDH3, His Tag with the EC50 of 2.4ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Anti-CDH3 Antibody, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human CDH3, His Tag with the EC50 of 2.4ug/ml determined by ELISA.
The purity of Human CDH3 is greater than 95% as determined by SEC-HPLC.
Human CDH3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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