Product Description |
Recombinant Human CDH3/Cadherin 3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp108-Gly654. |
Product Background |
Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been proved it could be a serum marker to monitor colorectal cancer. Inhibited CDH3 expression could upregulate E-cadherin, downregulated N-cadherin, which may control invasion and migration. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
CDH3/Cadherin 3 |
Synonyms |
Cadherin-3;Placental cadherin;P-cadherin;CDH3;CDHP;HJMD;PCAD;PCADP-cadherin;CAD3 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Asp108-Gly654 |
Molecular Weight |
The protein has a predicted MW of 64.32 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Anti-CDH3 Antibody, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human CDH3, His Tag with the EC50 of 1.12ug/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
-20 to -80°C for 24 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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