Human GPC3 VLP (GPC-HE005) Summary
Product Description |
Recombinant Human GPC3 VLP is expressed from E.coli.It contains Gly510-Asn554. |
Product Background |
Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed. |
Product Category |
Recombinant Protein / Antibody discovery, Cell therapy / ADC targets |
Human GPC3 VLP (GPC-HE005) Specifications/Details
Protein |
GPC3/Glypican 3 |
Synonyms |
GPC3; DGSX; Glypican 3; GTR2-2; MXR7; OCI5; OCI-5; SGB; SGBS; SGBS1SDYS; SDYS; SGBS1 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly510-Asn554 |
Molecular Weight |
The target protein has a predicted MW of 14 kDa. |
Activity |
Immobilized Human GPC3 VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-GPC3 Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. |
Expression System |
E.coli |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in 20mM HEPES, 500mM NaCl, 10% Glycerol, 0.1% Tween20 (pH 7.7). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Human GPC3 VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-GPC3 Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. |
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