- Express System: HEK293
- Purity: > 95% as determined by HPLC
- Activity: Immobilized Biotinylated Human Claudin 6 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test). The affinity constant of 0.16 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Amino Acid Range: Met1-Val220
Product Description |
Recombinant Biotinylated Full length Human Claudin 6 Protein-VLP is expressed from HEK293.It contains Met1-Val220. |
Product Background |
Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP |
Protein |
Claudin 6 |
Synonyms |
Claudin-6; Skullin; CLDN6; Claudin6; Skullin 2 |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Met1-Val220 |
Molecular Weight |
The target protein has a predicted MW of 24.5 kDa. |
Activity |
Immobilized Biotinylated Human Claudin 6 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test). The affinity constant of 0.16 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Expression System |
HEK293 |
Purity |
> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in PBS, 300mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Additional Information
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