Biotinylated Human Claudin 6 Protein-VLP (CLD-HM006B)

  • Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Biotinylated: yes
  • Activity: The affinity constant of 0.65 nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Exact Sequence: Met1-Val220

Catalog: CLD-HM006B

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Product Description Recombinant Biotinylated Full length Human Claudin 6 Protein-VLP is expressed from HEK293.It contains Met1-Val220.

Product Background

Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.

Product Category

Recombinant Protein

Target

Claudin 6
Synonyms Claudin-6; Skullin; CLDN6; Claudin6; Skullin 2

Gene/Protein ID

P56747

Species

Human

Exact Sequence

Met1-Val220
Molecular Weight The target protein has a predicted MW of 24.5 kDa.

Activity

The affinity constant of 0.65 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Express System

HEK293
Purity > 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in PBS, 300mM L-arginine (pH 7.4).
Stability And Storage Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human Claudin 6 VLP captured on CM5 Chip via Streptavidin can bind Anti-Claudin6 Antibody with an affinity constant of 0.65 nM as determined in SPR assay (Biacore T200).
The purity of Biotinylated Human Claudin 6 VLP is greater than 95% as determined by SEC-HPLC.

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