Name: Biotinylated Human Claudin 6 VLP (CLD-HM006B)
Brand: KactusBio
SKU: CLD-HM006B-100UG
Price: 2165.9 USD
Availability: InStock

Biotinylated Human Claudin 6 VLP (CLD-HM006B)

Biotinylated Human Claudin 6 VLP captured on CM5 Chip via streptavidin can bind Anti-Claudin 6 Antibody with an affinity constant of 0.46 nM as determined in SPR assay (Biacore T200).

Immobilized Biotinylated Human Claudin 6 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test).

Loaded Biotinylated Human Claudin 6 VLP on Streptavidin-Biosensor can bind Anti-Claudin 6 Antibody, hFc Tag with an affinity constant of 1.46 nM as determined in BLI assay (Gator® Prime).

The purity of Biotinylated Human Claudin 6 VLP is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Purity: > 95% as determined by HPLC
Activity: Immobilized Biotinylated Human Claudin 6 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test). The affinity constant of 0.46 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Met1-Val220

Catalog #CLD-HM006B

Size

100UG

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Biotinylated Human Claudin 6 VLP (CLD-HM006B) Summary

Product Description	Recombinant Biotinylated Full length Human Claudin 6 VLP is expressed from HEK293.It contains Met1-Val220 (It may have cross reaction with anti-His antibody).
Product Background	Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP

Biotinylated Human Claudin 6 VLP (CLD-HM006B) Specifications/Details

Protein	Claudin 6
Synonyms	Claudin-6; Skullin; CLDN6; Claudin6; Skullin 2
Accession	P56747
Species	Human
Biotinylated	yes
Amino Acid Range	Met1-Val220
Molecular Weight	The target protein has a predicted MW of 24.5 kDa.
Activity	Immobilized Biotinylated Human Claudin 6 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test). The affinity constant of 0.46 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Expression System	HEK293
Purity	> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in PBS, 300mM L-arginine (pH 7.4).
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Biotinylated Human Claudin 6 VLP captured on CM5 Chip via streptavidin can bind Anti-Claudin 6 Antibody with an affinity constant of 0.46 nM as determined in SPR assay (Biacore T200).
	Immobilized Biotinylated Human Claudin 6 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test).
	Loaded Biotinylated Human Claudin 6 VLP on Streptavidin-Biosensor can bind Anti-Claudin 6 Antibody, hFc Tag with an affinity constant of 1.46 nM as determined in BLI assay (Gator® Prime).
	The purity of Biotinylated Human Claudin 6 VLP is greater than 95% as determined by SEC-HPLC.