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Biotinylated Human Claudin 1 Nanodisc (CLD-HM1N1B) Summary
Product Description |
Recombinant Biotinylated Human Claudin 1 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val211. |
Product Background |
Claudin-1 (CLDN1), a major component of tight junction complexes in the epithelium, maintains cellular polarity, and plays a critical role in cell-to-cell communication as well as epithelial cell homeostasis. Moreover, CLDN1 expression is up-regulated in several cancers, and the level of CLDN1 expression has been proposed as a prognostic marker of patient survival. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc |
Biotinylated Human Claudin 1 Nanodisc (CLD-HM1N1B) Specifications/Details
Protein |
Claudin 1 |
Synonyms |
Claudin-1; CLDN1; CLD1; SEMP1 |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Met1-Val211 |
Molecular Weight |
The protein has a predicted MW of 35.69 kDa. |
Activity |
Immobilized Biotinylated Human Claudin 1 Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin 1 Antibody, hFc Tag with the EC50 of 15.9ng/ml determined by ELISA. |
Product Tag |
C-His |
Fluorophore |
Biotin-labeled |
Expression System |
HEK293 |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Biotinylated Human Claudin 1 Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin 1 Antibody, hFc Tag with the EC50 of 15.9ng/ml determined by ELISA. |
Other Available Proteins:
Finding available proteins...
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