Human CXCR6 VLP (CXC-HM1R6) Summary
Product Description |
Recombinant Human CXCR6 VLP is expressed from HEK293.It contains Met1-Leu342 (It may have cross reaction with anti-His antibody). |
Product Background |
CXCR6 is a receptor for the chemokine CXCL16, which exists as a membrane or soluble form. CXCR6 is a marker for resident memory T (TRM) cells that plays a role in immunosurveillance through their interaction with epithelial cells. The interaction of CXCR6 with CXCL16 expressed at the membrane of certain subpopulations of intratumor dendritic cells (DC) called DC3, ideally positions these CXCR6+ T cells to receive a proliferation signal from IL-15 also presented by DC3. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP |
Human CXCR6 VLP (CXC-HM1R6) Specifications/Details
Protein |
CXCR6 |
Synonyms |
CXC-R6; CXCR-6; CDw186; CD186; BONZO; STRL33; TYMSTR |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Leu342 |
Molecular Weight |
The target protein has a predicted MW of 42.49 kDa. |
Activity |
Immobilized Human CXCR6 VLP at 5 ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR6 Antibody, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA. |
Expression System |
HEK293 |
Purity |
> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Human CXCR6 VLP at 5 ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR6 Antibody, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA. |
|
|
Human CXCR6 VLP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recently viewed
