Regular price
$600.00
Order by 4pm ET for delivery on:
Human Kallikrein 2/KLK2 Protein (pro form) (KLK-HM12P) Summary
Product Description |
Recombinant Human Kallikrein 2/KLK2 Protein (pro form) is expressed from HEK293 with His tag at the C-terminus. The protein needs to be activated by Trypsin for an activated form.It contains Pro19-Pro261 with modified propeptide. |
Product Background |
Kallikrein-related peptidase 2 (KLK2) is a serine protease exhibiting antiangiogenic properties through proteolytic activity. KLK2 is overexpressed in prostate cancer and plays a pivotal role in cancer progression, establishing it as a potential therapeutic target. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Human Kallikrein 2/KLK2 Protein (pro form) (KLK-HM12P) Specifications/Details
Protein |
Kallikrein 2/KLK2 |
Synonyms |
KLK2; Kallikrein 2; hGK-1; hK2; KLK2A2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Pro19-Pro261 |
Molecular Weight |
The protein has a predicted MW of 28.43 kDa. Due to glycosylation, the protein migrates to 28-38 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human Kallikrein 2 (pro form), His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kallikrein 2 Antibody, hFc Tag with the EC50 of 3.9ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave the fluorogenic peptide substrate: PFR-AMC. The specific activity is >150 pmol/min/µg. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in 20mM Tris, 150mM NaCl, 8% trehalose (pH 8.0). |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Human Kallikrein 2 (pro form), His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kallikrein 2 Antibody, hFc Tag with the EC50 of 3.9ng/ml determined by ELISA. |
|
|
Human Kallikrein 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human Kallikrein 2 is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recommended Products
Loading...
Recently viewed
