Name: Biotinylated Human/Cynomolgus Activin RIIA/ACVR2A Protein (ARA-HM42AB)
Brand: KactusBio
SKU: ARA-HM42AB-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human/Cynomolgus Activin RIIA/ACVR2A Protein (ARA-HM42AB)

Biotinylated Human/Cynomolgus Activin RIIA, His Tag immobilized on CM5 Chip can bind Human Activin A, No Tag with an affinity constant of 0.10 nM as determined in SPR assay (Biacore T200).

Immobilized Human/Mouse/Rat Activin A, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIA, His Tag with the EC50 of 0.23 ug/ml determined by ELISA.

Biotinylated Human/Cynomolgus Activin RIIA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human/Cynomolgus Activin RIIA is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human/Mouse/Rat Activin A, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIA, His Tag with the EC50 of 0.23 ug/ml determined by ELISA. The affinity constant of 0.10 nM as determined in SPR assay (Biacore T200).
Amino Acid Range: Ala20-Pro135

Catalog #ARA-HM42AB

Size

100UG

500UG

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Biotinylated Human/Cynomolgus Activin RIIA/ACVR2A Protein (ARA-HM42AB) Summary

Product Description	Recombinant Biotinylated Human/Cynomolgus Activin RIIA/ACVR2A Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Ala20-Pro135.
Product Background	Activin A receptor type 2A (ACVR2A) is a membrane receptor in the transforming growth factor- beta (TGF-β signaling pathway, which is involved in the regulation of cell proliferation, migration, and apoptosis. Loss of ACVR2A has an important role in cancer progression and distant metastasis and may serve as a prognostic marker in patients with colon cancer.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Biotinylated Human/Cynomolgus Activin RIIA/ACVR2A Protein (ARA-HM42AB) Specifications/Details

Protein	Activin RIIA/ACVR2A
Synonyms	ACTR-IIA; ACTRIIA; ACVR2A; ACVR2
Accession	P27037-1(Human) / G7PKJ4(Cynomolgus)
Species	Human/Cynomolgus
Biotinylated	yes
Amino Acid Range	Ala20-Pro135
Molecular Weight	The protein has a predicted MW of 16.31 kDa. Due to glycosylation, the protein migrates to 30-45 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human/Mouse/Rat Activin A, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIA, His Tag with the EC50 of 0.23 ug/ml determined by ELISA. The affinity constant of 0.10 nM as determined in SPR assay (Biacore T200).
Product Tag	C-His-Avi
Fluorophore	Biotin-labeled
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Biotinylated Human/Cynomolgus Activin RIIA, His Tag immobilized on CM5 Chip can bind Human Activin A, No Tag with an affinity constant of 0.10 nM as determined in SPR assay (Biacore T200).
	Immobilized Human/Mouse/Rat Activin A, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIA, His Tag with the EC50 of 0.23 ug/ml determined by ELISA.
	Biotinylated Human/Cynomolgus Activin RIIA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human/Cynomolgus Activin RIIA is greater than 95% as determined by SEC-HPLC.

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Biotinylated Human/Cynomolgus Activin RIIA/ACVR2A Protein (ARA-HM42AB)

Biotinylated Human/Cynomolgus Activin RIIA/ACVR2A Protein (ARA-HM42AB)

Biotinylated Human/Cynomolgus Activin RIIA/ACVR2A Protein (ARA-HM42AB) Summary

Product Description

Product Background

Product Category

Biotinylated Human/Cynomolgus Activin RIIA/ACVR2A Protein (ARA-HM42AB) Specifications/Details

Fluorophore

Shipping, Reconstitution, & Storage

Validation Images

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