- Express System: HEK293
- Product Tag: C-His-Avi
- Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
- Activity: Immobilized Biotinylated Human ALK-7, His-Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-ALK7 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test). See testing image for detail.
- Amino Acid Range: Glu21-Glu113
Product Description |
Recombinant Biotinylated Human ALK-7/Activin RIC Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Glu21-Glu113. |
Product Background |
Arterial stiffness is an important feature of diabetic macrovascular complications. Activin receptor-like kinase 7 (ALK7), a member of type I transforming growth factor-β (TGF-β) receptors, is correlated with pathogenic risks of type 2 diabetes mellitus and cardiovascular diseases and may be involved in cardiovascular remodeling. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
ALK-7/Activin RIC |
Synonyms |
ACTR-IC; ACVR1C; ALK7; Activin R1C; |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Glu21-Glu113 |
Molecular Weight |
The protein has a predicted MW of 13.71 kDa. Due to glycosylation, the protein migrates to 20-40 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Biotinylated Human ALK-7, His-Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-ALK7 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His-Avi |
Expression System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 20mM Tris, 150mM NaCl (pH 7.5). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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