Name: Human ACVR1/Activin RI Protein (ALK-HM202)
Brand: KactusBio
SKU: ALK-HM202-100UG
Price: 346.5 USD
Availability: InStock

SEC-HPLC chromatogram showing a major peak at 8.5 minutes and a minor peak at 7.8 minutes, indicating a highly pure protein sample with minimal aggregation.

Human ACVR1/Activin RI Protein (ALK-HM202)

Human ACVR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human ACVR1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Met21-Glu123

Catalog #ALK-HM202

Size

100UG

500UG

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Human ACVR1/Activin RI Protein (ALK-HM202) Summary

Product Description	Recombinant Human ACVR1/Activin RI Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Met21-Glu123.
Product Background	Activin A receptor type I (ACVR1), a transmembrane serine/threonine kinase, belongs to the transforming growth factor-β superfamily, which signals via phosphorylating the downstream effectors and SMAD transcription factors. Genetic variation in ACVR1 has been associated with a rare disease, fibrodysplasia ossificans progressive, and its somatic alteration is reported in rare cancer diffuse intrinsic pontine glioma.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human ACVR1/Activin RI Protein (ALK-HM202) Specifications/Details

Protein	ACVR1/ALK-2
Synonyms	Activin RIA; ACTR-I; ALK-2; ACVR1; SKR1; TSR-I; ACVRLK2; Activin RI; Activin R1; ACVR1A
Accession	Q04771
Species	Human
Biotinylated	no
Amino Acid Range	Met21-Glu123
Molecular Weight	The protein has a predicted MW of 37.43 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human ACVR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ACVR1 is greater than 95% as determined by SEC-HPLC.