Name: Human ACVR1/Activin RI Protein (ALK-HM202)
Brand: KactusBio
SKU: ALK-HM202-100UG
Price: 315.0 USD
Availability: InStock

Human ACVR1/Activin RI Protein (ALK-HM202)

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Met21-Glu123

Catalog #ALK-HM202

Size

100UG

500UG

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Product Description	Recombinant Human ACVR1/Activin RI Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Met21-Glu123.
Product Background	Activin A receptor type I (ACVR1), a transmembrane serine/threonine kinase, belongs to the transforming growth factor-β superfamily, which signals via phosphorylating the downstream effectors and SMAD transcription factors. Genetic variation in ACVR1 has been associated with a rare disease, fibrodysplasia ossificans progressive, and its somatic alteration is reported in rare cancer diffuse intrinsic pontine glioma.
Product Category	Recombinant Protein

Target	ACVR1/ALK-2
Synonyms	ACTR-I; ALK-2; ACVR1; SKR1; TSR-I; ACVRLK2; Activin RI; Activin R1
Accession	Q04771
Species	Human
Biotinylated	no
Amino Acid Range	Met21-Glu123
Molecular Weight	The protein has a predicted MW of 37.43 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Human ACVR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ACVR1 is greater than 95% as determined by SEC-HPLC.

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