Name: Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein (ARB-HM52BB)
Brand: KactusBio
SKU: ARB-HM52BB-100UG
Price: 525.0 USD
Availability: InStock

Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein (ARB-HM52BB)

Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 26.2ng/ml determined by ELISA (QC Test).

Immobilized Anti-Activin RIIB Antibody, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 9.1ng/ml determined by ELISA.

Biotinylated Human/Cynomolgus Activin RIIB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human/Cynomolgus Activin RIIB is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 26.2ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Ser19-Thr137 (Human) / Ser40-Thr158 (Cynomolgus)

Catalog #ARB-HM52BB

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein is expressed from HEK293 with hFc tag and Avi tag at the C-terminus.It contains Ser19-Thr137 (Human) / Ser40-Thr158 (Cynomolgus).
Product Background	ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9).
Product Category	Recombinant Protein / Antibody discovery

Protein	Activin RIIB/ACVR2B
Synonyms	Activin receptor type-2B; ACVR2B; Activin RIIB
Accession	Q13705-1(Human) / XP_045242398.1(Cynomolgus)
Species	Human/Cynomolgus
Biotinylated	yes
Amino Acid Range	Ser19-Thr137 (Human) / Ser40-Thr158 (Cynomolgus)
Molecular Weight	The protein has a predicted MW of 41.41 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 26.2ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-hFc-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 26.2ng/ml determined by ELISA (QC Test).
	Immobilized Anti-Activin RIIB Antibody, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 9.1ng/ml determined by ELISA.
	Biotinylated Human/Cynomolgus Activin RIIB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human/Cynomolgus Activin RIIB is greater than 95% as determined by SEC-HPLC.