Name: Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein (Primary Amine Labeling) (ARB-HM32BB)
Brand: KactusBio
SKU: ARB-HM32BB-100UG
Price: 577.5 USD
Availability: InStock

ELISA dose-response curve demonstrating the binding interaction between biotinylated human/cynomolgus Activin RIIB, mFc tag, and immobilized human Activin A, with increasing receptor concentrations corresponding to higher OD450 absorbance.

Immobilized Human Activin A, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, mFc Tag with the EC50 of 37.8ng/ml determined by ELISA (QC Test).

Biotinylated Human/Cynomolgus Activin RIIB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-mFc
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human Activin A, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, mFc Tag with the EC50 of 37.8ng/ml determined by ELISA (QC Test).
Amino Acid Range: Ser19-Thr137 (Human) / Ser40-Thr158 (Cynomolgus)

Catalog #ARB-HM32BB

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein (Primary Amine Labeling) (ARB-HM32BB) Summary

Product Description	Recombinant Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein (Primary Amine Labeling) is expressed from HEK293 with mFc (IgG1) tag at the C-terminus.It contains Ser19-Thr137 (Human) / Ser40-Thr158 (Cynomolgus).
Product Background	ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9).
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein (Primary Amine Labeling) (ARB-HM32BB) Specifications/Details

Protein	Activin RIIB/ACVR2B
Synonyms	Activin receptor type-2B; ACVR2B; Activin RIIB; ActRIIB
Accession	Q13705-1(Human) / XP_045242398.1(Cynomolgus)
Species	Human/Cynomolgus
Biotinylated	yes
Amino Acid Range	Ser19-Thr137 (Human) / Ser40-Thr158 (Cynomolgus)
Molecular Weight	The protein has a predicted MW of 39.32 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Activin A, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, mFc Tag with the EC50 of 37.8ng/ml determined by ELISA (QC Test).
Product Tag	C-mFc
Fluorophore	Biotin-labeled
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human Activin A, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, mFc Tag with the EC50 of 37.8ng/ml determined by ELISA (QC Test).
	Biotinylated Human/Cynomolgus Activin RIIB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Other Available Proteins:

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Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein (Primary Amine Labeling) (ARB-HM32BB)

Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein (Primary Amine Labeling) (ARB-HM32BB)

Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein (Primary Amine Labeling) (ARB-HM32BB) Summary

Product Description

Product Background

Product Category

Biotinylated Human/Cynomolgus Activin RIIB/ACVR2B Protein (Primary Amine Labeling) (ARB-HM32BB) Specifications/Details

Fluorophore

Shipping, Reconstitution, & Storage

Validation Images

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