Name: GMP Human IL-21 (GMP-CKS-HE021)
Brand: KactusBio
SKU: GMP-CKS-HE021-50UG
Price: 440.0 USD
Availability: InStock

Catalog #GMP-CKS-HE021

Size

50UG

50UGX10

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GMP Human IL-21 (GMP-CKS-HE021) Summary

Product Description	Recombinant GMP Human IL-21 is expressed from E.coli with without tag.It contains Gln32-Ser162.
Product Background	Interleukin- (IL-) 21 is a pleiotropic cytokine that regulates the activity of both innate and specific immunity. Indeed, it costimulates T and natural killer (NK) cell proliferation and function and regulates B cell survival and differentiation and the function of dendritic cells. In addition, IL-21 exerts divergent effects on different lymphoid cell leukemia and lymphomas, as it may support cell proliferation or on the contrary induce growth arrest or apoptosis of the neoplastic lymphoid cells.
Product Category	Recombinant Protein / Cell therapy / Cell culture / Cytokines

GMP Human IL-21 (GMP-CKS-HE021) Specifications/Details

Protein	IL-21
Synonyms	Interleukin-21; IL-21; Za11; CVID11
Accession	Q9HBE4-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln32-Ser162
Molecular Weight	The protein has a predicted MW of 15.4 kDa same as Bis-Tris PAGE result.
Product Tag	No Tag
Expression System	E.coli
Purity	≥ 95% as determined by SEC-HPLC.
Endotoxin	≤ 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Please refer to the Certificate of Analysis for detailed instructions.
Stability And Storage	The product is shipped with ice bag. Store it immediately at -20°C±5°C upon arrival.；-20°C±5°C for 36 months in lyophilized state.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	GMP Human IL-21 on Bis-Tris PAGE under reduced condition.
	Measured by its activity to enhance IFN-gamma secretion in NK-92 human natural killer lymphoma cells. The ED50 for this effect is ≤ 8 ng/mL. The specific activity of GMP Human IL-21 is > 1 × 10^5-U/mg (QC Test).