Product Description |
Recombinant Human ALK-7/Activin RIC Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Glu21-Glu113. |
Product Background |
Arterial stiffness is an important feature of diabetic macrovascular complications. Activin receptor-like kinase 7 (ALK7), a member of type I transforming growth factor-β (TGF-β) receptors, is correlated with pathogenic risks of type 2 diabetes mellitus and cardiovascular diseases and may be involved in cardiovascular remodeling. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
ALK-7/Activin RIC |
Synonyms |
ACTR-IC; ACVR1C; ALK7; Activin R1C; |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu21-Glu113 |
Molecular Weight |
The protein has a predicted MW of 35.96 kDa. Due to glycosylation, the protein migrates to 48-60 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human ALK-7, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-ALK-7 Antibody, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-hFc |
Expression System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 0.1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Immobilized Human ALK-7, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-ALK-7 Antibody, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA (QC Test). |
|
|
Human ALK-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human ALK-7 is greater than 95% as determined by SEC-HPLC. |
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