Name: Human ALK-7/Activin RIC Protein, Ultra Low Endotoxin (ALK-HM107-UL)
Brand: KactusBio
SKU: ALK-HM107-UL-100UG
Price: 327.0 USD
Availability: InStock

Human ALK-7/Activin RIC Protein, Ultra Low Endotoxin (ALK-HM107-UL)

Anti-ALK-7 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Human ALK-7, His Tag with an affinity constant of 0.67 nM as determined in SPR assay (Biacore T200).

Immobilized Human ALK-7, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ALK-7 Antibody, hFc Tag with the EC50 of 3.15ng/ml determined by ELISA (QC Test).

Human ALK-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human ALK-7 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human ALK-7, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ALK-7 Antibody, hFc Tag with the EC50 of 3.15ng/ml determined by ELISA (QC Test). The affinity constant of 0.67 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Glu21-Glu113

Catalog #ALK-HM107-UL

Size

100UG

500UG

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Product Description	Recombinant Human ALK-7/Activin RIC Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu21-Glu113.
Product Background	Arterial stiffness is an important feature of diabetic macrovascular complications. Activin receptor-like kinase 7 (ALK7), a member of type I transforming growth factor-β (TGF-β) receptors, is correlated with pathogenic risks of type 2 diabetes mellitus and cardiovascular diseases and may be involved in cardiovascular remodeling.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	ALK-7/Activin RIC
Synonyms	ACTR-IC; ACVR1C; ALK7; Activin R1C;
Accession	Q8NER5-1
Species	Human
Biotinylated	no
Amino Acid Range	Glu21-Glu113
Molecular Weight	The protein has a predicted MW of 11.11 kDa. Due to glycosylation, the protein migrates to 20-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human ALK-7, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ALK-7 Antibody, hFc Tag with the EC50 of 3.15ng/ml determined by ELISA (QC Test). The affinity constant of 0.67 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20mM Tris, 150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Anti-ALK-7 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Human ALK-7, His Tag with an affinity constant of 0.67 nM as determined in SPR assay (Biacore T200).
	Immobilized Human ALK-7, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ALK-7 Antibody, hFc Tag with the EC50 of 3.15ng/ml determined by ELISA (QC Test).
	Human ALK-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ALK-7 is greater than 95% as determined by SEC-HPLC.