Product Description |
Recombinant Human ALK-7/Activin RIC Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu21-Glu113. |
Product Background |
Arterial stiffness is an important feature of diabetic macrovascular complications. Activin receptor-like kinase 7 (ALK7), a member of type I transforming growth factor-β (TGF-β) receptors, is correlated with pathogenic risks of type 2 diabetes mellitus and cardiovascular diseases and may be involved in cardiovascular remodeling. |
Product Category |
Recombinant Protein |
Target |
ALK-7/Activin RIC |
Synonyms |
ACTR-IC; ACVR1C; ALK7; Activin R1C; |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu21-Glu113 |
Molecular Weight |
The protein has a predicted MW of 11.11 kDa. Due to glycosylation, the protein migrates to 20-40 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in 20mM Tris, 150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human ALK-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human ALK-7 is greater than 95% as determined by SEC-HPLC. |
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