Name: Human ALK-7/Activin RIC Protein (ALK-HM107)
Brand: KactusBio
SKU: ALK-HM107-100UG
Price: 297.0 USD
Availability: InStock

SEC-HPLC chromatogram showing a single major protein peak at 9.483 minutes, indicating high purity of the analyzed protein sample.

Human ALK-7/Activin RIC Protein (ALK-HM107)

Anti-ALK-7 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Human ALK-7, His Tag with an affinity constant of 0.67 nM as determined in SPR assay (Biacore T200).

Immobilized Human ALK-7, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ALK-7 Antibody, hFc Tag with the EC50 of 3.15ng/ml determined by ELISA (QC Test).

Human ALK-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human ALK-7 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human ALK-7, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ALK-7 Antibody, hFc Tag with the EC50 of 3.15ng/ml determined by ELISA (QC Test). The affinity constant of 0.67 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Glu21-Glu113

Catalog #ALK-HM107

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Human ALK-7/Activin RIC Protein (ALK-HM107) Summary

Product Description	Recombinant Human ALK-7/Activin RIC Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu21-Glu113.
Product Background	Arterial stiffness is an important feature of diabetic macrovascular complications. Activin receptor-like kinase 7 (ALK7), a member of type I transforming growth factor-β (TGF-β) receptors, is correlated with pathogenic risks of type 2 diabetes mellitus and cardiovascular diseases and may be involved in cardiovascular remodeling.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human ALK-7/Activin RIC Protein (ALK-HM107) Specifications/Details

Protein	ALK-7/Activin RIC
Synonyms	ACTR-IC; ACVR1C; ALK7; Activin R1C;
Accession	Q8NER5-1
Species	Human
Biotinylated	no
Amino Acid Range	Glu21-Glu113
Molecular Weight	The protein has a predicted MW of 11.11 kDa. Due to glycosylation, the protein migrates to 20-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human ALK-7, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ALK-7 Antibody, hFc Tag with the EC50 of 3.15ng/ml determined by ELISA (QC Test). The affinity constant of 0.67 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20mM Tris, 150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Anti-ALK-7 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Human ALK-7, His Tag with an affinity constant of 0.67 nM as determined in SPR assay (Biacore T200).
	Immobilized Human ALK-7, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ALK-7 Antibody, hFc Tag with the EC50 of 3.15ng/ml determined by ELISA (QC Test).
	Human ALK-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ALK-7 is greater than 95% as determined by SEC-HPLC.