Name: Human/Cynomolgus Activin RIIA/ACVR2A-Protein, Ultra Low Endotoxin (ARA-HM12A-UL)
Brand: KactusBio
SKU: ARA-HM12A-UL-100UG
Price: 182.0 USD
Availability: InStock

Human/Cynomolgus Activin RIIA/ACVR2A-Protein, Ultra Low Endotoxin (ARA-HM12A-UL)

Human/Mouse/Rat GDF-8, No Tag immobilized on CM5 Chip can bind Human/Cynomolgus Activin RIIA, His Tag with an affinity constant of 0.87 uM as determined in SPR assay (Biacore T200).

Immobilized Human Activin A, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIA, His Tag with the EC50 of 0.23 ug/ml determined by ELISA (QC Test).

Human/Cynomolgus Activin RIIA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human/Cynomolgus Activin RIIA is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human Activin A, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIA, His Tag with the EC50 of 0.23 ug/ml determined by ELISA (QC Test). The affinity constant of 0.87 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Ala20-Pro135

Catalog #ARA-HM12A-UL

Size

100UG

500UG

Order now, ships by:

[{"id":47049776300254,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"ARA-HM12A-UL-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human\/Cynomolgus Activin RIIA\/ACVR2A-Protein, Ultra Low Endotoxin (ARA-HM12A-UL) - 100UG","public_title":"100UG","options":["100UG"],"price":18200,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":47049892790494,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"ARA-HM12A-UL-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human\/Cynomolgus Activin RIIA\/ACVR2A-Protein, Ultra Low Endotoxin (ARA-HM12A-UL) - 500UG","public_title":"500UG","options":["500UG"],"price":60500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Human/Cynomolgus Activin RIIA/ACVR2A-Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala20-Pro135.
Product Background	Activin A receptor type 2A (ACVR2A) is a membrane receptor in the transforming growth factor- beta (TGF-β signaling pathway, which is involved in the regulation of cell proliferation, migration, and apoptosis. Loss of ACVR2A has an important role in cancer progression and distant metastasis and may serve as a prognostic marker in patients with colon cancer.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	Activin RIIA/ACVR2A
Synonyms	ACTR-IIA; ACTRIIA; ACVR2A; ACVR2; ACTRII
Accession	P27037-1(Human) / G7PKJ4(Cynomolgus)
Species	Human/Cynomolgus
Biotinylated	no
Amino Acid Range	Ala20-Pro135
Molecular Weight	The protein has a predicted MW of 14.50 kDa. Due to glycosylation, the protein migrates to 30-45 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Activin A, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIA, His Tag with the EC50 of 0.23 ug/ml determined by ELISA (QC Test). The affinity constant of 0.87 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.001 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human/Mouse/Rat GDF-8, No Tag immobilized on CM5 Chip can bind Human/Cynomolgus Activin RIIA, His Tag with an affinity constant of 0.87 uM as determined in SPR assay (Biacore T200).
	Immobilized Human Activin A, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIA, His Tag with the EC50 of 0.23 ug/ml determined by ELISA (QC Test).
	Human/Cynomolgus Activin RIIA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human/Cynomolgus Activin RIIA is greater than 95% as determined by SEC-HPLC.