- Express System: HEK293
- Product Tag: C-His
- Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
- Activity: Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Rat Activin RIIB, His Tag with the EC50 of 12.7ng/ml determined by ELISA (QC Test). See testing image for detail.
- Amino Acid Range: Ser19-Thr137
Product Description |
Recombinant Rat Activin RIIB/ACVR2B Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser19-Thr137. |
Product Background |
ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9). |
Product Category |
Recombinant Protein |
Target |
Activin RIIB/ACVR2B |
Accession |
|
Species |
Rat |
Biotinylated |
no |
Amino Acid Range |
Ser19-Thr137 |
Molecular Weight |
The protein has a predicted MW of 15.29 kDa. Due to glycosylation, the protein migrates to 30-50 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Rat Activin RIIB, His Tag with the EC50 of 12.7ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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