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MRGPRX2: A Promising Target for Antibody Discovery in Allergy and Pain Disorders

Recent studies have shown that various drugs, including small molecules, opioids, and antibiotics, can activate MRGPRX2 (Mas-related G-protein coupled receptor X2), leading to mast cell degranulation and...

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Full Portfolio of In Vitro mRNA Synthesis Enzymes Submitted to FDA Drug Master Files (DMF)

April 23, 2023

2 min read

Contact us to request a quote or test sample!   Following the filings of our GMP-Grade BsaI and GMP-Grade T7...

New target for colorectal cancer: GPA33

February 24, 2023

4 min read

Colorectal cancer (CRC) is the third most common tumor and the most common tumor of the digestive system. With the...

Potential drug target for tumors: CDCP1

February 21, 2023

5 min read

The process of tumor cell infiltration, adhesion and migration is an important research direction in the process of drug development....

Cell and antibody therapies targeting HLA-G

February 14, 2023

3 min read

On December 19, 2022, the FDA approved the Phase I/IIa clinical trial application of IVS-3001, an anti-HLA-G CAR-T cell therapy...

A next-generation immunotherapy target TNFR2

February 10, 2023

5 min read

The tumor necrosis factor (TNF) superfamily has important physiological significance in immune surveillance, tumor regression, resistance to infection and hematopoiesis....

New Products February 2023

February 7, 2023

4 min read

Alkaline Phosphatase  Alkaline Phosphatase (ALP) likely represents the most frequently assayed enzyme in all of medicine. It is widely distributed...

GARP-TGF-β1 Monoclonal Antibody Clinical Trial Approved by FDA

January 23, 2023

3 min read

On January 4, 2023, Shanghai Jiyu Pharmaceutical announced that the IND application for its Class 1 drug JYB1907, GARP-TGF-β1 monoclonal...

Focus on hematoma target FLT3

January 9, 2023

6 min read

About FLT3 Fms-like tyrosine kinase 3 (FLT3) is also known as CD135 (Cluster of differentiation antigen 135) and FLK2 (Fetal...

DKK1: A Wnt Pathway Regulator

January 6, 2023

5 min read

DKK1 (Dickkopf-related protein 1, or Soggy) is a secreted glycoprotein that contains two conserved cysteine-rich domains CRD-1 and CRD-2 (also...

BsaI and T7 RNA Polymerase of KACTUS Pass FDA DMF Filing

January 4, 2023

2 min read

After successful completion of DMF filings for our CRISPR Cas9 enzyme and Maxnuclease in the first half of 2022, we...

TCR therapy targeting MAGE-A4

January 2, 2023

1 min read

Figure 1. MAGE-A4 Protein Recently at the 2022 CTOS Conference, Adaptimmune announced the SPEARHEAD-1 clinical trial data of its TCR-T...

CD163 Protein

November 17, 2022

KACTUS offers human, mouse, and biotinylated CD163 protein.  The hemoglobin (Hb) scavenger receptor CD163, is a macrophage-specific protein involved in...

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