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MRGPRX2: A Promising Target for Antibody Discovery in Allergy and Pain Disorders

Recent studies have shown that various drugs, including small molecules, opioids, and antibiotics, can activate MRGPRX2 (Mas-related G-protein coupled receptor X2), leading to mast cell degranulation and...

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Engineered T7 RNA Polymerase to Reduce dsRNA

May 24, 2023

1 min read

Our Chief Technology Officer, ManHee Suh, recently presented at the NextGen RNA Summit in Boston, MA his talk on "Engineered...

Full Portfolio of In Vitro mRNA Synthesis Enzymes Submitted to FDA Drug Master Files (DMF)

April 23, 2023

2 min read

Contact us to request a quote or test sample!   Following the filings of our GMP-Grade BsaI and GMP-Grade T7...

New target for colorectal cancer: GPA33

February 24, 2023

4 min read

Colorectal cancer (CRC) is the third most common tumor and the most common tumor of the digestive system. With the...

Potential drug target for tumors: CDCP1

February 21, 2023

5 min read

The process of tumor cell infiltration, adhesion and migration is an important research direction in the process of drug development....

Cell and antibody therapies targeting HLA-G

February 14, 2023

3 min read

On December 19, 2022, the FDA approved the Phase I/IIa clinical trial application of IVS-3001, an anti-HLA-G CAR-T cell therapy...

A next-generation immunotherapy target TNFR2

February 10, 2023

5 min read

The tumor necrosis factor (TNF) superfamily has important physiological significance in immune surveillance, tumor regression, resistance to infection and hematopoiesis....

New Products February 2023

February 7, 2023

4 min read

Alkaline Phosphatase  Alkaline Phosphatase (ALP) likely represents the most frequently assayed enzyme in all of medicine. It is widely distributed...

GARP-TGF-β1 Monoclonal Antibody Clinical Trial Approved by FDA

January 23, 2023

3 min read

On January 4, 2023, Shanghai Jiyu Pharmaceutical announced that the IND application for its Class 1 drug JYB1907, GARP-TGF-β1 monoclonal...

Focus on hematoma target FLT3

January 9, 2023

6 min read

About FLT3 Fms-like tyrosine kinase 3 (FLT3) is also known as CD135 (Cluster of differentiation antigen 135) and FLK2 (Fetal...

DKK1: A Wnt Pathway Regulator

January 6, 2023

5 min read

DKK1 (Dickkopf-related protein 1, or Soggy) is a secreted glycoprotein that contains two conserved cysteine-rich domains CRD-1 and CRD-2 (also...

BsaI and T7 RNA Polymerase of KACTUS Pass FDA DMF Filing

January 4, 2023

2 min read

After successful completion of DMF filings for our CRISPR Cas9 enzyme and Maxnuclease in the first half of 2022, we...

TCR therapy targeting MAGE-A4

January 2, 2023

1 min read

Figure 1. MAGE-A4 Protein Recently at the 2022 CTOS Conference, Adaptimmune announced the SPEARHEAD-1 clinical trial data of its TCR-T...

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