Name: Human HAI-1 Protein (HAI-HM11A)
Brand: KactusBio
SKU: HAI-HM11A-100UG
Price: 346.5 USD
Availability: InStock

Catalog #HAI-HM11A

Size

100UG

500UG

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Product Description	Recombinant Human HAI-1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly36-Val433.
Product Background	SPINT1, also known as HAI-1, is a Kunitz-type serine protease inhibitor that inhibits multiple proteases including hepatocyte growth factor (HGF) activator and matriptase. SPINT1 has been shown to modulate HGF/MET activation in certain cancer types.
Product Category	Recombinant Protein / Antibody discovery

Protein	HAI-1
Synonyms	HAI 1; SPINT1; HAI1; HAI-1
Accession	O43278-2
Species	Human
Biotinylated	no
Amino Acid Range	Gly36-Val433
Molecular Weight	The protein has a predicted MW of 45.50 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human HAI-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-Arg-Pro-Lys-Pro-Val-Glu-NVAL-Trp-Arg-Lys(DNP)-NH2. The IC50 is < 1 nM.
	The purity of Human HAI-1 is greater than 95% as determined by SEC-HPLC.