Human IL-17F Protein (ILF-HM119)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IL-17F, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17 R alpha, hFc Tag with the EC50 of 0.25ug/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Arg31-Gln163

Catalog: ILF-HM119

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Product Description Recombinant Human IL-17F Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg31-Gln163.

Product Background

The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable sequence divergence at the N‑terminus.IL-17F is ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover.

Product Category

Recombinant Protein

Target

IL-17F
Synonyms Cytokine ML-1; IL17F; IL-17F; IL24; IL-24; CANDF6; IL-17F; ML1

Gene/Protein ID

Q96PD4

Species

Human

Exact Sequence

Arg31-Gln163
Molecular Weight The protein has a predicted MW of 17.5 kDa. Due to glycosylation, the protein migrates to 23-28 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human IL-17F, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17 R alpha, hFc Tag with the EC50 of 0.25ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human IL-17F, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17 R alpha, hFc Tag with the EC50 of 0.25ug/ml determined by ELISA.
The purity of Human IL-17F is greater than 95% as determined by SEC-HPLC.
Human IL-17F on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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