Product Description |
Recombinant Human IL-17Rc Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Arg467. |
Product Background |
IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
IL-17Rc |
Synonyms |
IL-17 receptor C; IL-17RC; IL17Rhom; IL-17RL; ZcytoR14 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Leu21-Arg467 |
Molecular Weight |
The protein has a predicted MW of 76.2 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 33.8ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-hFc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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