• Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 54.6ng/ml determined by ELISA.
  • Amino Acid Range: Leu21-Arg467
Catalog #IL1-HM2RC
Price
Regular price $34650
Regular price Sale price $34650
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Size
Avantor VWR Fisher Scientific

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Human IL-17Rc Protein (IL1-HM2RC) Summary

Product Description

 Recombinant Human IL-17Rc Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Leu21-Arg467.

Product Background

 IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.

Human IL-17Rc Protein (IL1-HM2RC) Specifications/Details

Protein
 IL-17Rc
Synonyms
 IL-17 receptor C; IL-17RC; IL17Rhom; IL-17RL; ZcytoR14;IL17 receptor C; IL17RC; IL17RL
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Leu21-Arg467
Molecular Weight
 The protein has a predicted MW of 76.2 kDa. Due to glycosylation, the protein migrates to 95-135 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 54.6ng/ml determined by ELISA.
Product Tag
 C-hFc (IgG1)
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 54.6ng/ml determined by ELISA. Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 54.6ng/ml determined by ELISA.
Immobilized Human IL-25, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 4.64ug/ml determined by ELISA Immobilized Human IL-25, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 4.64ug/ml determined by ELISA
Immobilized Human IL-17F, His Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 90.7ng/ml determined by ELISA. Immobilized Human IL-17F, His Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 90.7ng/ml determined by ELISA.
Human IL-17Rc on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human IL-17Rc on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Other Available Proteins:
Finding available proteins...