Name: Human IL-17Rc Protein (IL1-HM2RC)
Brand: KactusBio
SKU: IL1-HM2RC-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 54.6ng/ml determined by ELISA.
Amino Acid Range: Leu21-Arg467

Catalog #IL1-HM2RC

Size

100UG

500UG

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Human IL-17Rc Protein (IL1-HM2RC) Summary

Product Description	Recombinant Human IL-17Rc Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Leu21-Arg467.
Product Background	IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Human IL-17Rc Protein (IL1-HM2RC) Specifications/Details

Protein	IL-17Rc
Synonyms	IL-17 receptor C; IL-17RC; IL17Rhom; IL-17RL; ZcytoR14
Accession	NP_703190.2
Species	Human
Biotinylated	no
Amino Acid Range	Leu21-Arg467
Molecular Weight	The protein has a predicted MW of 76.2 kDa. Due to glycosylation, the protein migrates to 95-135 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 54.6ng/ml determined by ELISA.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 54.6ng/ml determined by ELISA.
	Immobilized Human IL-25, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 4.64ug/ml determined by ELISA
	Human IL-17Rc on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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