Human IL-17Rc Protein (IL1-HM2RC)
Human IL-17Rc Protein (IL1-HM2RC)
Human IL-17Rc Protein (IL1-HM2RC)
Human IL-17Rc Protein (IL1-HM2RC)
Human IL-17Rc Protein (IL1-HM2RC)
Human IL-17Rc Protein (IL1-HM2RC)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 33.8ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Leu21-Arg467
Catalog #IL1-HM2RC
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Product Description
 Recombinant Human IL-17Rc Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Arg467.
Product Background
 IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.
Product Category
 Recombinant Protein
Target
 IL-17Rc
Synonyms
 IL-17 receptor C; IL-17RC; IL17Rhom; IL-17RL; ZcytoR14
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Leu21-Arg467
Molecular Weight
 The protein has a predicted MW of 76.2 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 33.8ng/ml determined by ELISA. See testing image for detail.
Product Tag
 C-hFc
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human IL-17A, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 33.8ng/ml determined by ELISA.
Human IL-17Rc on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-17Rc is greater than 95% as determined by SEC-HPLC.
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