Human LGR-5 Protein-Nanodisc (LR5-HM1N157)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-5 Nanodisc, His Tag with the EC50 of 0.68ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Met1-Leu907
Catalog #LR5-HM1N157
Regular price $1,444.30
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Product Description

Recombinant Human LGR-5 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Leu907.

Product Background

G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker and prognostic indicator that can promote EMT by activating the Wnt/β-catenin pathway and would thus be a novel therapeutic target for glioma.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc
Protein
LGR-5
Synonyms
LGR5; GPR49; GPR67; HG38; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Leu907
Molecular Weight
The protein has a predicted MW of 101.35 kDa.
Activity
Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-5 Nanodisc, His Tag with the EC50 of 0.68ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-His
Expression System
HEK293
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-5 Nanodisc, His Tag with the EC50 of 0.68ug/ml determined by ELISA. Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-5 Nanodisc, His Tag with the EC50 of 0.68ug/ml determined by ELISA.
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