Product Description |
Recombinant Human LIF R/CD118 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln45-Ser833. |
Product Background |
The leukemia inhibitory factor receptor (LIF-R) subunit is a component of cell-surface receptor complexes for the multifunctional cytokines, LIF, cardiotrophin-1, ciliary neurotrophic factor, and human oncostatin M. The structure of the human LIF-R gene is similar to that of the mouse gene. The transmembrane receptor is encoded by 19 exons. |
Product Category |
Recombinant Protein |
Target |
LIF R/CD118 |
Synonyms |
FLJ99923; SJS2; STWS; SWS; LIFR; CD118; FLJ98106 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln45-Ser833 |
Molecular Weight |
The protein has a predicted MW of 116.1 kDa. Due to glycosylation, the protein migrates to 120-160 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human LIF, No Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human LIF R, hFc Tag with the EC50 of 66.8ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCL, 200mM L-arginine, 5mM DTT. |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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|
Immobilized Human LIF, No Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human LIF R, hFc Tag with the EC50 of 66.8ng/ml determined by ELISA. |
|
|
Human LIF R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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