Human Osteoactivin/GPNMB Protein (GNB-HM101)
Human Osteoactivin/GPNMB Protein (GNB-HM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Lys23-Asn486
Catalog #GNB-HM101
Regular price $300.00
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Product Description
Recombinant Human Osteoactivin/GPNMB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys23-Asn486.
Product Background
GPNMB is highly expressed in macrophages and microglia, which are cells involved with innate immune response in the periphery and the brain, respectively. Some studies have shown increased levels of GPNMB in pro-inflammatory conditions, such as LPS treatment, and in pathological conditions, such as neurodegenerative diseases and cancer.
Product Category
Recombinant Protein
Target
Osteoactivin/GPNMB
Synonyms
GPNMB; HGFIN; NMB; Osteoactivin
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Lys23-Asn486
Molecular Weight
The protein has a predicted MW of 53.1 kDa. Due to glycosylation, the protein migrates to 78-98 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human Osteoactivin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human Osteoactivin is greater than 95% as determined by SEC-HPLC.

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