Name: Human Osteoactivin/GPNMB Protein (GNB-HM101)
Brand: KactusBio
SKU: GNB-HM101-100UG
Price: 330.0 USD
Availability: InStock

SEC-HPLC chromatogram showing a single major peak at approximately 8 minutes for protein purity analysis of recombinant product.

Human Osteoactivin/GPNMB Protein (GNB-HM101)

Human Osteoactivin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Amino Acid Range: Lys23-Asn486

Catalog #GNB-HM101

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Human Osteoactivin/GPNMB Protein (GNB-HM101) Summary

Product Description	Recombinant Human Osteoactivin/GPNMB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys23-Asn486.
Product Background	GPNMB is highly expressed in macrophages and microglia, which are cells involved with innate immune response in the periphery and the brain, respectively. Some studies have shown increased levels of GPNMB in pro-inflammatory conditions, such as LPS treatment, and in pathological conditions, such as neurodegenerative diseases and cancer.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Human Osteoactivin/GPNMB Protein (GNB-HM101) Specifications/Details

Protein	Osteoactivin/GPNMB
Synonyms	GPNMB; HGFIN; NMB; Osteoactivin
Accession	NP_002501.1
Species	Human
Biotinylated	no
Amino Acid Range	Lys23-Asn486
Molecular Weight	The protein has a predicted MW of 53.1 kDa. Due to glycosylation, the protein migrates to 78-98 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.