- Express System: HEK293
- Product Tag: C-His
- Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
- Activity: Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIB, His Tag with the EC50 of 22.1ng/ml determined by ELISA. See testing image for detail.
- Amino Acid Range: Ser19-Thr137
Product Description |
Recombinant Mouse Activin RIIB/ACVR2B Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser19-Thr137. |
Product Background |
ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9). |
Product Category |
Recombinant Protein |
Target |
Activin RIIB/ACVR2B |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ser19-Thr137 |
Molecular Weight |
The protein has a predicted MW of 14.78 kDa. Due to glycosylation, the protein migrates to 30-50 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIB, His Tag with the EC50 of 22.1ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recently viewed