Mouse Activin RIIB/ACVR2B Protein (ARB-MM12B)
Mouse Activin RIIB/ACVR2B Protein (ARB-MM12B)
Mouse Activin RIIB/ACVR2B Protein (ARB-MM12B)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIB, His Tag with the EC50 of 22.1ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Ser19-Thr137
Catalog #ARB-MM12B
Regular price $270.00
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Product Description
Recombinant Mouse Activin RIIB/ACVR2B Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser19-Thr137.
Product Background
ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9).
Product Category
Recombinant Protein
Target
Activin RIIB/ACVR2B
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Ser19-Thr137
Molecular Weight
The protein has a predicted MW of 14.78 kDa. Due to glycosylation, the protein migrates to 30-50 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIB, His Tag with the EC50 of 22.1ng/ml determined by ELISA. See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIB, His Tag with the EC50 of 22.1ng/ml determined by ELISA.
Mouse Activin RIIB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse Activin RIIB is greater than 95% as determined by SEC-HPLC.

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