Mouse IL-17RB Protein (IL1-MM1RB)
Mouse IL-17RB Protein (IL1-MM1RB)
Mouse IL-17RB Protein (IL1-MM1RB)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Arg18-Gly286
Catalog #IL1-MM1RB
Regular price $270.00
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Product Description
Recombinant Mouse IL-17RB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg18-Gly286.
Product Background
Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.
Product Category
Recombinant Protein
Target
IL-17RB
Synonyms
IL-17 receptor B; IL-17RB; IL-17ER; Evi27; IL-17 RH1; IL-17ER; IL17RB
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Arg18-Gly286
Molecular Weight
The protein has a predicted MW of 30.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse IL-17RB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-17RB is greater than 95% as determined by SEC-HPLC.

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