• Express System: HEK293
  • Product Tag: N-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gln73-Gln269
Catalog #CLE-MM201
Price
Regular price $297.00
Regular price Sale price $297.00
/
Size
Avantor VWR Fisher Scientific

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Mouse CLEC-1 Protein (CLE-MM201) Summary

Product Description

 Recombinant Mouse CLEC-1 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Gln73-Gln269.

Product Background

 C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis.

Mouse CLEC-1 Protein (CLE-MM201) Specifications/Details

Protein
 CLEC-1
Synonyms
 CLEC-1; CLEC1; CLEC1A; MGC34328
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Gln73-Gln269
Molecular Weight
 The protein has a predicted MW of 50.4 kDa. Due to glycosylation, the protein migrates to 66-68 kDa based on Bis-Tris PAGE result.
Product Tag
 N-hFc (IgG1)
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse CLEC-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse CLEC-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse CLEC-1 is greater than 95% as determined by SEC-HPLC. The purity of Mouse CLEC-1 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...