• Express System: HEK293
  • Product Tag: N-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Thr47-Ser173
Catalog #FSF-MM218
Price
Regular price $313.50
Regular price Sale price $313.50
/
Size
Avantor VWR Fisher Scientific

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Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218) Summary

Product Description

 Recombinant Mouse GITR Ligand/TNFSF18 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Thr47-Ser173.

Product Background

 Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.

Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218) Specifications/Details

Protein
 GITR Ligand/TNFSF18
Synonyms
 TNFSF18; AITRL; TL6; GITRL; GITR Ligand
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Thr47-Ser173
Molecular Weight
 The protein has a predicted MW of 41.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Product Tag
 N-hFc (IgG1)
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse GITR Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse GITR Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse GITR Ligand is greater than 95% as determined by SEC-HPLC. The purity of Mouse GITR Ligand is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...