• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser21-Thr367
Catalog #IL1-MM1R3
Price
Regular price $181.50
Regular price Sale price $181.50
/
Size
Avantor VWR Fisher Scientific

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Mouse IL-1R3/IL-1 RAcP Protein (IL1-MM1R3) Summary

Product Description

 Recombinant Mouse IL-1R3/IL-1 RAcP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser21-Thr367.

Product Background

 Interleukin (IL)-1R3 is the co-receptor in three signaling pathways that involve six cytokines of the IL-1 family (IL-1α, IL-1β, IL-33, IL-36α, IL-36β and IL-36γ). In many diseases, multiple cytokines contribute to disease pathogenesis. For example, in asthma, both IL-33 and IL-1 are of major importance, as are IL-36 and IL-1 in psoriasis.

Mouse IL-1R3/IL-1 RAcP Protein (IL1-MM1R3) Specifications/Details

Protein
 IL-1R3/IL-1 RAcP
Synonyms
 IL1RAP; C3orf13; IL-1 R3; IL-1 RAcP;IL1R3; IL1RAcP
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Ser21-Thr367
Molecular Weight
 The protein has a predicted MW of 41.1 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse IL-1R3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IL-1R3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-1R3 is greater than 95% as determined by SEC-HPLC. The purity of Mouse IL-1R3 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...