• Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Arg60-Ile363
Catalog #LOX-MM101
Price
Regular price $29700
Regular price Sale price $29700
/
Size
Avantor VWR Fisher Scientific

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Mouse LOX1 Protein (LOX-MM101) Summary

Product Description

 Recombinant Mouse LOX1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Arg60-Ile363.

Product Background

 LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion also results in damage from ischemia, making LOX-1 a promising target of therapy for atherosclerosis and related disorders. In this article we focus on the different mechanisms for regulation, signaling and the various effects of LOX-1 in contributing to atherosclerosis.

Mouse LOX1 Protein (LOX-MM101) Specifications/Details

Protein
 LOX1
Synonyms
 Ox-LDL receptor 1; LOX-1; CLEC8A; LOX1; OLR1; LOXIN; SR-E1; SCARE1; SLOX1
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Arg60-Ile363
Molecular Weight
 The protein has a predicted MW of 36.1 kDa. Due to glycosylation, the protein migrates to 55-63 kDa based on Bis-Tris PAGE result.
Product Tag
 N-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse LOX1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse LOX1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse LOX1 is greater than 95% as determined by SEC-HPLC. The purity of Mouse LOX1 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...