• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Cynomolgus LRIG1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LRIG1 Antibody, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA.
  • Amino Acid Range: Ala34-Thr792
Catalog #LRI-CM101
Price
Regular price $37500
Regular price Sale price $37500
/
Size
Avantor VWR Fisher Scientific

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Cynomolgus LRIG1 Protein (LRI-CM101) Summary

Product Description

 Recombinant Cynomolgus LRIG1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala34-Thr792.

Product Background

 The leucine-rich repeats and immunoglobulin-like domains (LRIG)-1 is a tumor suppressor gene that belongs to the LRIG family. LRIG1 expression has prognostic significance in various human cancers. Somatic mutations, which are associated with a certain rate of response to targeted therapies, are ubiquitously found in human non-small cell lung cancer (NSCLC). LRIG1 was an independent prognostic factor for OS of NSCLC patients. LRIG1 in combination with other clinicopathological risk factors was a stronger prognostic model than clinicopathological risk factors alone.

Cynomolgus LRIG1 Protein (LRI-CM101) Specifications/Details

Protein
 LRIG1
Synonyms
 LIG-1; LIG1; LRIG1; D6Bwg0781e; Img
Accession
Species
 Cynomolgus
Biotinylated
 no
Amino Acid Range
 Ala34-Thr792
Molecular Weight
 The protein has a predicted MW of 84.16 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Cynomolgus LRIG1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LRIG1 Antibody, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS, 200mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Cynomolgus LRIG1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LRIG1 Antibody, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA. Immobilized Cynomolgus LRIG1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LRIG1 Antibody, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA.
Cynomolgus LRIG1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus LRIG1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Other Available Proteins:
Finding available proteins...