Human TRAIL R3/DcR1 Protein (TRA-HM103) Summary
Product Description |
Recombinant Human TRAIL R3/DcR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr24-Ala236. |
Product Background |
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family, which mediates apoptosis by the extrinsic pathway. Up-regulation of decoy receptors, DcR1 and DcR2, may result in diminished binding of TRAIL to their functional receptors. DcR1 expression occurs in a subset of EC and may contribute to resistance to TRAIL-induced apoptosis. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Human TRAIL R3/DcR1 Protein (TRA-HM103) Specifications/Details
Protein |
TRAIL R3/DcR1 |
Synonyms |
CD263; DCR1; DCR1-TNFR; LIT; TRAIL-R3; TRAILR3; TRID; TNFRSF10C;DCR1TNFR |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Tyr24-Ala236 |
Molecular Weight |
The protein has a predicted MW of 23.5 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins:
Finding available proteins...