• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 17.39 µM as determined in SPR assay (Biacore T200).
  • Amino Acid Range: Ala21-Arg200
Catalog #TRM-HM101
Price
Regular price $346.50
Regular price Sale price $346.50
/
Size
Avantor VWR Fisher Scientific

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Human TREM1 Protein (TRM-HM101) Summary

Product Description

 Recombinant Human TREM1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala21-Arg200.

Product Background

 TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a pro-inflammatory receptor expressed by phagocytes, which can also be released as a soluble molecule (sTREM1). The roles of TREM1 and sTREM1 in liver infection and inflammation are not clear.

Human TREM1 Protein (TRM-HM101) Specifications/Details

Protein
 TREM1
Synonyms
 CD354; TREM-1;TREM1
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Ala21-Arg200
Molecular Weight
 The protein has a predicted MW of 21.4 kDa. Due to glycosylation, the protein migrates to 30-50 kDa based on Bis-Tris PAGE result.
Activity
 The affinity constant of 17.39 µM as determined in SPR assay (Biacore T200).
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human PGLYRP1, hFc Tag (Cat. PGL-HM201) captured on CM5 Chip via Protein A can bind Human TREM1, His Tag with an affinity constant of 17.39 µM as determined in SPR assay (Biacore T200). Human PGLYRP1, hFc Tag (Cat. PGL-HM201) captured on CM5 Chip via Protein A can bind Human TREM1, His Tag with an affinity constant of 17.39 µM as determined in SPR assay (Biacore T200).
Human TREM1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human TREM1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Loaded Human TREM1, His Tag on Anti-His-Biosensor can bind Human PGLYRP1, hFc Tag (Cat. PGL-HM201) with an affinity constant of 32.90 nM as determined in BLI assay. Loaded Human TREM1, His Tag on Anti-His-Biosensor can bind Human PGLYRP1, hFc Tag (Cat. PGL-HM201) with an affinity constant of 32.90 nM as determined in BLI assay.
The purity of Human TREM1 is greater than 95% as determined by SEC-HPLC. The purity of Human TREM1 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...