• Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 0.17 uM as determined in SPR assay (Biacore T200).
  • Amino Acid Range: His31-Asp225
Catalog #ULB-HM204
Price
Regular price $346.50
Regular price Sale price $346.50
/
Size
Avantor VWR Fisher Scientific

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Human ULBP-4 Protein (ULB-HM204) Summary

Product Description

 Recombinant Human ULBP-4 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains His31-Asp225.

Product Background

 UL16-binding proteins (ULBPs) are markers of cellular stress which are upregulated on the surface of virus-infected and tumor cells. ULBPs are expressed by a variety of leukemias, carcinomas, melanomas, and tumor cell lines.ULBP4 is associated with higher levels of CD8+/NKG2D+ lymphocytes infiltrating the carcinoma and is a prognosticator of improved survival.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human ULBP-4 Protein (ULB-HM204) Specifications/Details

Protein
 ULBP-4
Synonyms
 N2DL-4; NKG2DL4; RAE-1-like transcript 4; RAET1E; LETAL; N2DL4; ULBP4;
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 His31-Asp225
Molecular Weight
 The protein has a predicted MW of 49.12 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity
 The affinity constant of 0.17 uM as determined in SPR assay (Biacore T200).
Product Tag
 C-hFc (IgG1)

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human ULBP-4, hFc Tag captured on CM5 Chip via Protein A can bind Human NKG2D, His Tag with an affinity constant of 0.17 uM as determined in SPR assay (Biacore T200). Human ULBP-4, hFc Tag captured on CM5 Chip via Protein A can bind Human NKG2D, His Tag with an affinity constant of 0.17 uM as determined in SPR assay (Biacore T200).
Human ULBP-4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human ULBP-4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human ULBP-4 is greater than 95% as determined by SEC-HPLC. The purity of Human ULBP-4 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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